The combination drug preparation containing Salmeterol Xinafoate and fluticasone propionate is an effective medication that provides symptomatic relief and prevents Asthma, Chronic bronchitis and chronic disorders of pulmonary glands. This drug is used for controlling and preventing the symptoms caused by asthma like wheezing and shortness of breath. Fluticasone is a corticosteroid while Salmeterol is a long acting beta antagonist. It prevents the asthma attack for asthma sufferers and decreases the inflammation in the lungs by releasing the chemicals that opens up the constricted tubes. This Inhaler is a preventive medicine and is not effective when asthma attack has already begun. It contains active ingredient Salbutamol in it, which has a relaxing effect on the constricted bronchioles. It is a short acting beta receptor agonist and exerts bronchodilator effects. It stimulates the beta 2 receptors and relaxes the smooth muscles of all airways from the trachea to the terminal bronchioles. Along with this, it also stops the production of inflammatory cell mediators that causes constriction. It also increases self clearing mechanism of bronchi. This ingredient helps in relaxing the constricted bronchioles and facilitates the smooth breathing. While on the other hand the other combination ingredient works by reducing swelling and irritation of the airways.