Benoquin Cream (Monobenzone Cream) is used for depigmentation of the skin as a treatment for widespread vitiligo, a skin condition in which irregular patches of skin, covering about 50% of the body surface, lose color and become whitened. This is caused by destruction of the pigment producing cells called melanocytes. Monobenzone Cream is used as a skin lightener in people with vitiligo, to reduce the colour of patches of skin that contain pigment so that they match the areas of skin that have lost colour. Decolouration of the skin using Monobenzone Cream is permanent and makes the skin sensitive to sunburn. Benoquin cream contains monobenzone (monobenzyl ether of hyquinone) that works by causing free-radical formation in the skin and this causes destruction of remaining melanocytes. Monobenzone in Benoquin cream also acts by inhibiting the tyrosine enzyme that is involved in the production of melanin, the pigment that gives colour to the skin. As the amount of melanin produced decreases the areas of normal skin gradually lighten to match the patches of vitiliginous paler skin.